HitPredict

Interactor 1: MECOM (Q03112)
Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1)
Gene: MECOM

Interactor 2: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1230 Hs			1 680
+	Hs
		1059881 PRD16_HUMAN (1-1230): 0: 813: 44.40		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		974566 MECOM_HUMAN (1-1230): 0: 666: 90.02		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		974543 MECOM_HUMAN (1-1230): 0: 666: 90.02		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		563803 ZNF43_HUMAN (7-500): 1.95e-162: 506: 19.06		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		1128450 ZN484_HUMAN (2-430): 1.39e-140: 449: 21.62		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		170388 ZN484_HUMAN (2-430): 1.39e-140: 449: 21.62		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		64157 ZN726_HUMAN (700-1229): 3.49e-124: 398: 14.03		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		164497 ZN629_HUMAN (14-493): 1.75e-106: 358: 12.40		TRI66_HUMAN (2-647): 2.96e-69: 248: 14.35
+	Hs
		170186 ZN254_HUMAN (10-316): 9.39e-87: 297: 15.84		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170415 ZN695_HUMAN (881-1093): 5.71e-30: 127: 18.28		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170346 ZN543_HUMAN (440-867): 1.71e-23: 108: 9.28		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170423 ZN383_HUMAN (770-935): 1.34e-18: 92.4: 17.58		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170255 ZNF10_HUMAN (782-960): 1.81e-17: 89.7: 14.69		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		1314779 ZN416_HUMAN (908-991): 1.33e-09: 64.3: 39.29		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		170480 ZN287_HUMAN (6-107): 1.07e-09: 65: 8.74		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170465 ZN416_HUMAN (908-991): 1.33e-09: 64.3: 39.29		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		1059638 ZKSC8_HUMAN (92-289): 6.95e-10: 65.1: 15.39		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		1018504 ZKSC8_HUMAN (92-289): 6.95e-10: 65.1: 15.39		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21