HitPredict

Interactor 1: GNA12 (Q03113)
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Gene: GNA12

Interactor 2: ARHG1 (Q92888)
Rho guanine nucleotide exchange factor 1 (115 kDa guanine nucleotide exchange factor) (p115-RhoGEF) (p115RhoGEF) (Sub1.5)
Gene: ARHGEF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 14634662, 20300064
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~RGS-like, G-alpha~RhoGEF
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007266 - Rho protein signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 381
Hs

1 912
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024