HitPredict

Interactor 1: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15657086
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001935 - endothelial cell proliferation GO:0005886 - plasma membrane GO:0005901 - caveola GO:0009267 - cellular response to starvation GO:0010628 - positive regulation of gene expression and 1 others more... GO:0016324 - apical plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 1038
+	Mm
		193109 CAV1_MOUSE (1-178): 4.63e-108: 308: 94.94		BMPR2_MOUSE (1-1038): 0: 868: 96.63
+	Hs
		337434 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		ABL1_HUMAN (166-1016): 1.93e-137: 444: 15.47
+	Hs
		738335 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75
+	Hs
		739955 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		TGFR2_HUMAN (8-521): 1.09e-118: 378: 29.66
+	Mm
		835146 CAV1_MOUSE (1-178): 4.63e-108: 308: 94.94		TGFR1_MOUSE (59-504): 2.76e-112: 358: 28.72
+	Hs
		738531 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Hs
		739524 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		ACVL1_HUMAN (50-512): 1.08e-98: 322: 28.37