HitPredict

Interactor 1: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4

Interactor 2: EPHA2 (Q03145)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK) (Tyrosine-protein kinase receptor MPK-5) (Tyrosine-protein kinase receptor SEK-2)
Gene: EPHA2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16977320
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains EphA2_TM~PK_Tyr_Ser-Thr, Ephrin_lbd~Ephrin_lbd, Ephrin_lbd~fn3, fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1, SAM_1~SAM_2
Common GO terms GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 986
Mm

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Last updated: 15 Jul 2024