HitPredict

Interactor 1: SNO1 (Q03144)
Pyridoxal 5'-phosphate synthase subunit SNO1 (EC 4.3.3.6) (PDX2 homolog 1) (Pdx2.1) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)
Gene: SNO1

Interactor 2: SNZ1 (Q03148)
Pyridoxal 5'-phosphate synthase subunit SNZ1 (PLP synthase subunit SNZ1) (EC 4.3.3.6) (PDX1 homolog 1) (Pdx1.1) (p35)
Gene: SNZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.921

Property	Details
Experiments	11283351, 10688190, 14764090, 9791124, 18719252
Identification Methods	two hybrid pooling approach, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SNO~SOR_SNZ
Common GO terms	GO:0006543 - glutamine catabolic process GO:0008615 - pyridoxine biosynthetic process GO:0036381 - pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity GO:0042819 - vitamin B6 biosynthetic process GO:0042823 - pyridoxal phosphate biosynthetic process and 1 others more... GO:1903600 - glutaminase complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 224 Sc			1 297
+	Sc
		796982 SNO1_YEAST (1-224): 1.29e-124: 353: 100.00		SNZ3_YEAST (5-297): 5.02e-163: 456: 80.74
+	Sc
		865170 SNO1_YEAST (1-224): 1.29e-124: 353: 100.00		SNZ2_YEAST (5-297): 4.31e-163: 456: 80.41
+	Sc
		796976 SNO3_YEAST (15-222): 2.75e-102: 297: 67.14		SNZ1_YEAST (1-297): 1.1e-168: 471: 100.00
+	Sc
		865168 SNO2_YEAST (15-222): 5.49e-102: 296: 66.67		SNZ1_YEAST (1-297): 1.1e-168: 471: 100.00
+	Sc
		796972 SNO3_YEAST (15-222): 2.75e-102: 297: 67.14		SNZ3_YEAST (5-297): 5.02e-163: 456: 80.74
+	Sc
		796973 SNO3_YEAST (15-222): 2.75e-102: 297: 67.14		SNZ2_YEAST (5-297): 4.31e-163: 456: 80.41
+	Sc
		796978 SNO2_YEAST (15-222): 5.49e-102: 296: 66.67		SNZ3_YEAST (5-297): 5.02e-163: 456: 80.74
+	Sc
		865166 SNO2_YEAST (15-222): 5.49e-102: 296: 66.67		SNZ2_YEAST (5-297): 4.31e-163: 456: 80.41
+	At
		1226677 PDX2_ARATH (15-219): 2.01e-80: 242: 34.96		PDX13_ARATH (6-293): 2.75e-168: 470: 60.76
+	At
		285347 PDX2_ARATH (15-219): 2.01e-80: 242: 34.96		PDX11_ARATH (6-282): 2.72e-163: 457: 62.82
+	Sp
		144183 YFM8_SCHPO (3-222): 6.36e-80: 240: 37.72		PDX1_SCHPO (7-297): 1.6e-159: 447: 64.26
+	Pf
		86932 PDX2_PLAF7 (15-221): 4.41e-75: 227: 35.62		PDX1_PLAF7 (8-277): 5.88e-153: 431: 59.26
+	Bs
		741664 PDXT_BACSU (13-219): 6.72e-72: 218: 36.72		PDXS_BACSU (2-297): 1.43e-152: 430: 57.77
+	Ph
		223429 PDXT_PYRHO (16-222): 1.2e-76: 231: 40.67		PDXS_PYRHO (7-296): 1.37e-146: 416: 52.60