HitPredict

Interactor 1: RAC1 (Q03206)
Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)
Gene: ced-10

Interactor 2: VAV (Q45FX5)
Protein vav-1
Gene: vav-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16213217
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, PH~Ras, Ras~RhoGEF
Common GO terms	GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Ce			1 1007
+	Hs
		855782 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		VAV2_HUMAN (38-988): 4.13e-180: 548: 24.13
+	Hs
		548678 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		VAV_HUMAN (38-988): 9.12e-143: 449: 22.78
+	Mm
		925795 RAC1_MOUSE (1-191): 2.82e-82: 243: 82.81		TIAM1_MOUSE (147-605): 6.37e-73: 266: 18.78
+	Hs
		500934 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		MCF2_HUMAN (73-588): 5.54e-74: 265: 18.04
+	Hs
		224711 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		KALRN_HUMAN (213-819): 5.18e-72: 264: 19.68
+	Hs
		166482 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		MCF2L_HUMAN (94-761): 2.83e-72: 262: 14.82
+	Hs
		156397 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		RGRF2_HUMAN (81-881): 9.14e-71: 259: 11.74
+	Hs
		50555 RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87		PKHG3_HUMAN (243-589): 1.09e-70: 258: 22.57
+	Hs
		564502 RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87		TIAM1_HUMAN (121-680): 4.3e-70: 258: 17.22
+	Hs
		50580 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		PKHG3_HUMAN (243-589): 1.09e-70: 258: 22.57
+	Hs
		925241 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		TIAM1_HUMAN (121-680): 4.3e-70: 258: 17.22
+	Hs
		564737 RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87		PKHG1_HUMAN (203-812): 1.77e-69: 255: 17.12
+	Rn
		88818 RAC1_RAT (1-191): 2.82e-82: 243: 82.81		D3ZWV8_RAT (144-680): 1.28e-69: 256: 15.14
+	Hs
		924448 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		GRB2_HUMAN (801-990): 3.81e-74: 245: 30.73
+	Hs
		279854 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		TRIO_HUMAN (213-815): 1.31e-56: 216: 16.39
+	Hs
		564524 RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87		ARHG7_HUMAN (893-1006): 8.13e-15: 81: 24.56
+	Hs
		925271 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		ARHG7_HUMAN (893-1006): 8.13e-15: 81: 24.56
+	Hs
		564535 RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87		ARHG6_HUMAN (927-1004): 1.42e-11: 70.6: 24.36
+	Hs
		925289 RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81		ARHG6_HUMAN (927-1004): 1.42e-11: 70.6: 24.36
+	Gg
		1141019 Q6LC82_CHICK (1-191): 2.82e-82: 243: 82.81		ARHG6_CHICK (927-1004): 1.68e-10: 67.2: 25.64