HitPredict

Interactor 1: LMNB2 (Q03252)
Lamin-B2
Gene: LMNB2

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 620 Hs			1 2517
+	Hs
		360312 LMNA_HUMAN (24-614): 7.2e-59: 210: 51.78		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		595369 LMNB1_HUMAN (16-620): 4.22e-59: 209: 54.88		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		1205250 K2C73_HUMAN (38-405): 1.04e-52: 191: 22.22		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		443743 VIME_HUMAN (42-404): 6.17e-32: 130: 30.58		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		531540 K2C5_HUMAN (39-412): 3.22e-123: 378: 24.14		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		817952 LMNB2_HUMAN (1-620): 2.75e-70: 240: 100.00		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		595134 LMNB1_HUMAN (16-620): 4.22e-59: 209: 54.88		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		539724 LMNB1_MOUSE (21-620): 2.33e-60: 213: 54.67		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		360221 LMNA_HUMAN (24-614): 7.2e-59: 210: 51.78		BBX_HUMAN (1078-1189): 1.69e-34: 147: 48.21
+	Hs
		975642 LMNB2_HUMAN (1-620): 2.75e-70: 240: 100.00		SOX4_HUMAN (1091-1186): 2.77e-25: 114: 31.25
+	Mm
		589617 VIME_MOUSE (42-404): 2.3e-31: 129: 30.30		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		359942 LMNA_HUMAN (24-614): 7.2e-59: 210: 51.78		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Hs
		360546 LMNA_HUMAN (24-614): 7.2e-59: 210: 51.78		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		595471 LMNB1_HUMAN (16-620): 4.22e-59: 209: 54.88		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		360224 LMNA_HUMAN (24-614): 7.2e-59: 210: 51.78		TITIN_HUMAN (609-1544): 3.51e-09: 65.2: 9.85
+	Hs
		443800 VIME_HUMAN (42-404): 6.17e-32: 130: 30.58		TARA_HUMAN (523-2026): 3.76e-17: 91.1: 11.33
+	Hs
		443883 VIME_HUMAN (42-404): 6.17e-32: 130: 30.58		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		443464 VIME_HUMAN (42-404): 6.17e-32: 130: 30.58		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		965108 AINX_HUMAN (40-429): 3.53e-26: 114: 30.60		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		781878 PERI_HUMAN (2-404): 7.58e-26: 113: 29.83		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78