HitPredict

Interactor 1: HMSH (Q03372)
Muscle segmentation homeobox (Protein drop) (Protein msh)
Gene: Dr

Interactor 2: NOC (Q24423)
Zinc finger protein Noc (Zinc finger protein NocA)
Gene: NOC

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007420 - brain development GO:0010629 - negative regulation of gene expression
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 515 Dm			1 537
+	Dm
		949998 UBX_DROME (282-482): 1.56e-30: 124: 21.96		NOC_DROME (12-537): 1.28e-70: 237: 100.00
+	Hs
		724279 MSX2_HUMAN (347-496): 1.7e-33: 129: 53.29		ZN703_HUMAN (10-536): 3.38e-49: 180: 21.42
+	Hs
		679172 TLX1_HUMAN (377-491): 1.56e-30: 123: 35.35		ZN703_HUMAN (10-536): 3.38e-49: 180: 21.42
+	Hs
		211968 TLX3_HUMAN (266-513): 7.12e-30: 120: 21.71		ZN703_HUMAN (10-536): 3.38e-49: 180: 21.42
+	Hs
		882158 GSC_HUMAN (266-505): 3.66e-29: 117: 16.53		ZN703_HUMAN (10-536): 3.38e-49: 180: 21.42
+	Hs
		679137 TLX1_HUMAN (377-491): 1.56e-30: 123: 35.35		KMT2C_HUMAN (21-537): 7.52e-43: 166: 11.68
+	Hs
		211919 TLX3_HUMAN (266-513): 7.12e-30: 120: 21.71		KMT2C_HUMAN (21-537): 7.52e-43: 166: 11.68
+	Hs
		213358 TLX2_HUMAN (414-491): 5.26e-29: 117: 43.59		KMT2C_HUMAN (21-537): 7.52e-43: 166: 11.68
+	Hs
		882142 GSC_HUMAN (266-505): 3.66e-29: 117: 16.53		KMT2C_HUMAN (21-537): 7.52e-43: 166: 11.68
+	Hs
		679154 TLX1_HUMAN (377-491): 1.56e-30: 123: 35.35		ZN503_HUMAN (10-536): 2.95e-39: 153: 19.90
+	Hs
		211933 TLX3_HUMAN (266-513): 7.12e-30: 120: 21.71		ZN503_HUMAN (10-536): 2.95e-39: 153: 19.90
+	Hs
		882151 GSC_HUMAN (266-505): 3.66e-29: 117: 16.53		ZN503_HUMAN (10-536): 2.95e-39: 153: 19.90
+	Hs
		679182 TLX1_HUMAN (377-491): 1.56e-30: 123: 35.35		CHD7_HUMAN (153-511): 3e-12: 71.9: 12.40
+	Hs
		211986 TLX3_HUMAN (266-513): 7.12e-30: 120: 21.71		CHD7_HUMAN (153-511): 3e-12: 71.9: 12.40
+	Hs
		213398 TLX2_HUMAN (414-491): 5.26e-29: 117: 43.59		CHD7_HUMAN (153-511): 3e-12: 71.9: 12.40