HitPredict

Interactor 1: VPS72 (Q03388)
Vacuolar protein sorting-associated protein 72 (SWR complex protein 2)
Gene: VPS72

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.938

Property	Details
Experiments	16554755, 26831523, 31914392, 37968396, 14690608, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TIP49~YL1_C
Common GO terms	GO:0000785 - chromatin GO:0000812 - Swr1 complex GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 795 Sc			1 463
+	Sc
		976144 VPS72_YEAST (1-795): 0: 966: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Mm
		888067 VPS72_MOUSE (16-304): 5.58e-47: 173: 21.45		RUVB1_MOUSE (2-461): 0: 682: 67.83
+	Hs
		1079916 VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Hs
		1079915 VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Dm
		1366585 VPS72_DROME (17-315): 1e-38: 149: 25.75		RUVB1_DROME (15-461): 0: 648: 66.89