HitPredict - High confidence protein-protein interactions

Interactor 1: PCNA (Q03392)
Proliferating cell nuclear antigen (PCNA)
Gene: pcn1

Interactor 2: PCNA (Q03392)
Proliferating cell nuclear antigen (PCNA)
Gene: pcn1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.832

Property	Details
Experiments	26771498, 10698951, 7780738
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PCNA_C~PCNA_C, PCNA_C~PCNA_N, PCNA_N~PCNA_N
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 18 others more... GO:0006271 - DNA strand elongation involved in DNA replication GO:0006272 - leading strand elongation GO:0006298 - mismatch repair GO:0006301 - postreplication repair GO:0019985 - translesion synthesis GO:0030337 - DNA polymerase processivity factor activity GO:0035861 - site of double-strand break GO:0042276 - error-prone translesion synthesis GO:0043596 - nuclear replication fork GO:0043626 - PCNA complex GO:0045739 - positive regulation of DNA repair GO:0045740 - positive regulation of DNA replication GO:0070914 - UV-damage excision repair GO:0070987 - error-free translesion synthesis GO:0140861 - DNA repair-dependent chromatin remodeling GO:1900264 - positive regulation of DNA-directed DNA polymerase activity GO:1903459 - mitotic DNA replication lagging strand elongation GO:1903460 - mitotic DNA replication leading strand elongation
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	260
Sp

1	260

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Last updated: 15 Jul 2024