HitPredict

Interactor 1: MEF2D (Q03413)
Myocyte-specific enhancer factor 2D homolog (Serum response factor-like protein 1) (SL-1)
Gene: MEF2D

Interactor 2: HDAC9 (Q9YGY4)
Histone deacetylase 9 (EC 3.5.1.98) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	10487760
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 498 Xl			1 596
+	Hs
		880729 MEF2D_HUMAN (1-496): 9.45e-126: 378: 72.00		HDAC4_HUMAN (15-594): 0: 582: 45.99
+	Hs
		968804 MEF2A_HUMAN (1-498): 2.33e-106: 328: 53.54		HDAC9_HUMAN (29-594): 0: 606: 70.64
+	Hs
		987233 MEF2C_HUMAN (1-498): 5.55e-102: 315: 54.69		HDAC9_HUMAN (29-594): 0: 606: 70.64
+	Mm
		1144399 MEF2D_MOUSE (1-496): 1.85e-123: 372: 72.01		HDAC4_MOUSE (15-594): 0: 547: 44.72
+	Rn
		292567 MEF2D_RAT (1-496): 7.29e-119: 360: 70.85		HDAC4_RAT (15-594): 0: 552: 44.89
+	Hs
		880686 MEF2A_HUMAN (1-498): 2.33e-106: 328: 53.54		HDAC4_HUMAN (15-594): 0: 582: 45.99
+	Hs
		880693 MEF2C_HUMAN (1-498): 5.55e-102: 315: 54.69		HDAC4_HUMAN (15-594): 0: 582: 45.99
+	Mm
		1144402 MEF2D_MOUSE (1-496): 1.85e-123: 372: 72.01		HDAC9_MOUSE (29-595): 1.04e-180: 524: 69.20
+	Mm
		1141851 MEF2A_MOUSE (1-498): 2.92e-107: 330: 55.84		HDAC4_MOUSE (15-594): 0: 547: 44.72
+	Mm
		1157743 MEF2C_MOUSE (1-498): 5.07e-104: 321: 55.69		HDAC4_MOUSE (15-594): 0: 547: 44.72
+	Mm
		1112760 MEF2D_MOUSE (1-496): 1.85e-123: 372: 72.01		Q3UJF1_MOUSE (13-527): 7.15e-151: 464: 48.36
+	Hs
		1059602 MEF2D_HUMAN (1-496): 9.45e-126: 378: 72.00		HDAC5_HUMAN (14-527): 3.07e-148: 457: 49.46
+	Mm
		1144403 MEF2D_MOUSE (1-496): 1.85e-123: 372: 72.01		HDAC5_MOUSE (14-527): 3.74e-146: 452: 47.36
+	Mm
		1112756 MEF2A_MOUSE (1-498): 2.92e-107: 330: 55.84		Q3UJF1_MOUSE (13-527): 7.15e-151: 464: 48.36
+	Mm
		1112770 MEF2C_MOUSE (1-498): 5.07e-104: 321: 55.69		Q3UJF1_MOUSE (13-527): 7.15e-151: 464: 48.36
+	Hs
		968805 MEF2A_HUMAN (1-498): 2.33e-106: 328: 53.54		HDAC5_HUMAN (14-527): 3.07e-148: 457: 49.46
+	Mm
		1141852 MEF2A_MOUSE (1-498): 2.92e-107: 330: 55.84		HDAC7_MOUSE (102-586): 9.54e-118: 373: 24.41
+	Hs
		968793 MEF2A_HUMAN (1-498): 2.33e-106: 328: 53.54		HDAC7_HUMAN (102-586): 5.77e-118: 374: 25.60
+	Mm
		1207907 MEF2C_MOUSE (1-498): 5.07e-104: 321: 55.69		HDAC7_MOUSE (102-586): 9.54e-118: 373: 24.41
+	Hs
		987223 MEF2C_HUMAN (1-498): 5.55e-102: 315: 54.69		HDAC7_HUMAN (102-586): 5.77e-118: 374: 25.60