Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6
Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.760 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29225035, 31970402, 32355176, 20541997, 16916636, 7664335, 22032989, 26826127, 16751180, 29531219, 34526721, 37689310, 22902626 |
| Identification Methods | affinity chromatography technology, enzymatic study, proximity labelling technology, coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000012 - single strand break repair GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006283 - transcription-coupled nucleotide-excision repair GO:0006979 - response to oxidative stress and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
