HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20541997
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1493 Hs			1 129
+	Hs
		391663 ERCC6_HUMAN (1-1493): 0: 1168: 100.00		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391728 CHD9_HUMAN (3-1492): 0: 774: 18.73		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		1059647 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00
+	Hs
		1059717 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83
+	Hs
		1059795 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2A1H_HUMAN (1-127): 1.77e-65: 196: 96.06
+	Hs
		470387 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06
+	Hs
		391704 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		555466 CHD4_HUMAN (303-1439): 0: 766: 18.35		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		1018640 CHD3_HUMAN (303-1446): 0: 759: 19.68		H2A1H_HUMAN (1-127): 1.77e-65: 196: 96.06
+	Hs
		391675 CHD3_HUMAN (303-1446): 0: 759: 19.68		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391915 CHD8_HUMAN (2-1474): 0: 725: 16.46		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		555654 CHD8_HUMAN (2-1474): 0: 725: 16.46		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Sc
		392087 CHD1_YEAST (409-1426): 0: 748: 20.90		H2A1_YEAST (16-129): 1.56e-52: 163: 78.95
+	Sc
		392360 CHD1_YEAST (409-1426): 0: 748: 20.90		H2A2_YEAST (16-129): 1.63e-52: 163: 78.95
+	Hs
		229433 SMCA5_HUMAN (368-1383): 0: 698: 20.75		H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83
+	Hs
		470278 SMCA1_HUMAN (369-1372): 0: 700: 20.58		H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06
+	Hs
		229279 SMCA5_HUMAN (368-1383): 0: 698: 20.75		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		555306 SMCA1_HUMAN (369-1372): 0: 700: 20.58		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		229296 SMCA5_HUMAN (368-1383): 0: 698: 20.75		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		151474 CHD2_HUMAN (107-1433): 0: 681: 19.17		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49