Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 33288900
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom, SNF2-rel_dom~SNF2-rel_dom
Common GO terms GO:0003682 - chromatin binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0140658 - ATP-dependent chromatin remodeler activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1493
Hs

1 838
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024