HitPredict

Interactor 1: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2

Interactor 2: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19297616
Identification Methods cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0001913 - T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002237 - response to molecule of bacterial origin
GO:0002481 - antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
and 23 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 686
Hs

1 686
+ Rn
+ Rn
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Ce
+ Sc
+ Hs
+ Vc
+ Ec
+ Hs

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Last updated: 15 Jul 2024