HitPredict

Interactor 1: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	31511893, 16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Sc			1 459
+	Sc
		593714 DBP4_YEAST (3-501): 9.9e-165: 486: 37.70		NOP12_YEAST (1-459): 4.83e-75: 244: 100.00
+	Hs
		789439 DDX10_HUMAN (5-505): 1.4e-148: 448: 37.87		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Sc
		865748 HAS1_YEAST (1-505): 1.8e-165: 479: 100.00		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Hs
		133858 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		PABP1_HUMAN (175-459): 5.78e-60: 208: 14.58
+	Hs
		134018 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		PABP4_HUMAN (175-459): 6.56e-58: 203: 13.54
+	Hs
		134106 DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77		PABP2_HUMAN (252-400): 7.91e-43: 155: 25.49
+	Mm
		857323 DDX17_MOUSE (4-478): 4.53e-135: 406: 29.11		TIA1_MOUSE (273-459): 8.21e-34: 132: 12.23
+	Hs
		1077436 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Mm
		857351 Q8BTS0_MOUSE (4-449): 2.92e-131: 395: 30.22		TIA1_MOUSE (273-459): 8.21e-34: 132: 12.23
+	Hs
		571469 DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Mm
		936480 DDX5_MOUSE (4-449): 2.93e-131: 395: 30.22		TIAR_MOUSE (271-459): 4.76e-28: 116: 13.17
+	Hs
		1073611 DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31		SF3B4_HUMAN (269-458): 2.8e-22: 100: 14.56
+	Hs
		789546 DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Sc
		699738 DRS1_YEAST (26-394): 3.8e-72: 245: 38.32		NOP12_YEAST (1-459): 4.83e-75: 244: 100.00
+	Hs
		789505 DDX27_HUMAN (44-441): 4.37e-71: 243: 37.04		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Hs
		1063286 DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37		SART3_HUMAN (31-408): 3.53e-46: 173: 14.86
+	Hs
		1063282 DDX47_HUMAN (1-411): 5.57e-74: 242: 36.96		SART3_HUMAN (31-408): 3.53e-46: 173: 14.86
+	Sc
		699709 DRS1_YEAST (26-394): 3.8e-72: 245: 38.32		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Sc
		548430 MS116_YEAST (5-409): 4.69e-64: 221: 35.63		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Sc
		638828 SPB4_YEAST (56-488): 1.9e-61: 213: 33.41		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73