Interactor 1: CCDA (P62552)
Antitoxin CcdA (LynA) (Protein H) (Protein LetA)
Gene: CCDA
Interactor 2: CCDB (P62554)
Toxin CcdB (Cytotoxic protein CcdB) (LynB) (Protein G) (Protein LetD)
Gene: CCDB
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 0.90 | 0.702 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19647513 |
| Identification Methods | x-ray crystallography, molecular sieving, isothermal titration calorimetry, surface plasmon resonance, circular dichroism |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CcdA~CcdB |
| Common GO terms | GO:0017053 - transcription repressor complex GO:0045892 - negative regulation of DNA-templated transcription GO:0110001 - toxin-antitoxin complex |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
