Interactor 1: USA1 (Q03714)
U1 SNP1-associating protein 1
Gene: USA1
Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.55 | 0.720 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20005842, 16873066, 37968396, 19898607, 19394298, 37066402, 21074049, 16429126 |
| Identification Methods | pull down, affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000836 - Hrd1p ubiquitin ligase complex GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
