HitPredict

Interactor 1: GIS1 (Q03833)
Transcriptional activator/repressor GIS1
Gene: GIS1

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Sc			1 889
+	Sc
		696247 GIS1_YEAST (1-876): 2.01e-172: 524: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Mm
		1111955 KDM4C_MOUSE (4-634): 3.38e-131: 421: 18.92		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Mm
		1111958 KDM4B_MOUSE (4-821): 1.71e-122: 399: 15.60		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Mm
		1111949 KDM4A_MOUSE (2-816): 4.92e-122: 397: 15.59		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Mm
		101540 KDM4C_MOUSE (4-634): 3.38e-131: 421: 18.92		F8VQD1_MOUSE (3-125): 3.07e-19: 95.9: 20.64
+	Mm
		101541 KDM4B_MOUSE (4-821): 1.71e-122: 399: 15.60		F8VQD1_MOUSE (3-125): 3.07e-19: 95.9: 20.64
+	Mm
		101539 KDM4A_MOUSE (2-816): 4.92e-122: 397: 15.59		F8VQD1_MOUSE (3-125): 3.07e-19: 95.9: 20.64
+	Hs
		64157 ZN726_HUMAN (235-822): 6.22e-83: 281: 7.08		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22
+	Hs
		782323 KDM5C_HUMAN (8-81): 1.12e-17: 90.8: 24.32		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		244060 KDM5C_HUMAN (8-81): 1.12e-17: 90.8: 24.32		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		170346 ZN543_HUMAN (289-682): 1.83e-33: 139: 8.38		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22
+	Hs
		245058 KDM5B_HUMAN (5-94): 5.38e-17: 88.5: 23.33		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		170480 ZN287_HUMAN (272-668): 9.13e-31: 131: 7.37		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22
+	Hs
		998877 ZN444_HUMAN (830-875): 1.52e-09: 62.4: 52.17		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		631537 JARD2_HUMAN (9-102): 5.91e-11: 68.7: 21.28		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		782356 KDM5C_HUMAN (8-81): 1.12e-17: 90.8: 24.32		PB1_HUMAN (234-742): 1.78e-19: 96.7: 14.64
+	Hs
		782389 KDM5C_HUMAN (8-81): 1.12e-17: 90.8: 24.32		ASH1L_HUMAN (6-150): 7.87e-19: 94.7: 21.43
+	Hs
		666553 KDM5A_HUMAN (4-80): 6.11e-18: 91.5: 25.97		ZMYD8_HUMAN (19-121): 2.55e-15: 82.8: 20.00
+	Hs
		782398 KDM5C_HUMAN (8-81): 1.12e-17: 90.8: 24.32		ZMYD8_HUMAN (19-121): 2.55e-15: 82.8: 20.00
+	Hs
		170186 ZN254_HUMAN (272-635): 9.18e-18: 90.4: 7.49		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22