Interactor 1: E2AK2 (Q03963)
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Serine/threonine-protein kinase TIK) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
Gene: Eif2ak2
Interactor 2: NLRP3 (Q8R4B8)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22801494 |
| Identification Methods | anti bait coimmunoprecipitation, molecular sieving |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_6~Pkinase, NACHT~Pkinase |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
