HitPredict

Interactor 1: ARI5A (Q03989)
AT-rich interactive domain-containing protein 5A (ARID domain-containing protein 5A) (Modulator recognition factor 1) (MRF-1)
Gene: ARID5A

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 126
+	Hs
		918369 ARI5B_HUMAN (2-387): 1.11e-70: 249: 31.19		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1060138 ARI5B_HUMAN (2-387): 1.11e-70: 249: 31.19		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03
+	Hs
		1060146 ARI5B_HUMAN (2-387): 1.11e-70: 249: 31.19		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		1087459 KDM5B_HUMAN (21-319): 1.21e-62: 226: 16.26		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1087274 ARI1B_HUMAN (1-324): 4.28e-56: 207: 15.49		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1244294 ARI1B_HUMAN (1-324): 4.28e-56: 207: 15.49		H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03
+	Hs
		918640 ARI3A_HUMAN (4-233): 5.38e-43: 164: 18.03		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		146232 ARI1A_HUMAN (1-338): 6.15e-38: 152: 13.04		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		886168 JARD2_HUMAN (22-209): 1.12e-37: 151: 13.64		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		1271539 JARD2_HUMAN (22-209): 1.12e-37: 151: 13.64		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		666475 ARI4A_HUMAN (25-221): 5.8e-34: 140: 22.84		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		666487 ARI4A_HUMAN (25-221): 5.8e-34: 140: 22.84		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1087158 ARI4B_HUMAN (60-246): 1.2e-32: 136: 21.18		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918407 ARI4B_HUMAN (60-246): 1.2e-32: 136: 21.18		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087188 ARID2_HUMAN (52-162): 3.76e-31: 131: 29.46		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		707655 ARID2_HUMAN (52-162): 3.76e-31: 131: 29.46		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Zm
		17621 A0A1D6GXC6_MAIZE (22-314): 1.22e-34: 142: 10.54		B4FYZ0_MAIZE (2-125): 7.85e-44: 142: 65.32
+	Zm
		17631 A0A1D6GXC6_MAIZE (22-314): 1.22e-34: 142: 10.54		B6T1G5_MAIZE (14-125): 6.43e-44: 142: 69.64
+	Sc
		355306 SWI1_YEAST (42-150): 2.59e-25: 113: 27.52		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55