HitPredict

Interactor 1: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Interactor 2: NCBP2 (Q08920)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)
Gene: CBC2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24500206, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 859 Sc			1 208
+	Sc
		978490 SYF1_YEAST (1-859): 0: 548: 100.00		HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75
+	Hs
		1020334 SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48		ELAV2_HUMAN (4-155): 3.36e-22: 94.3: 16.13
+	Hs
		642766 SART3_HUMAN (398-838): 1.46e-44: 175: 13.31		ELAV4_HUMAN (4-187): 1.11e-23: 98.5: 15.05
+	Sc
		982907 RRP5_YEAST (572-839): 8.35e-22: 104: 15.96		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00
+	Sc
		586448 PRP6_YEAST (157-799): 5.81e-22: 103: 12.19		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00
+	Sp
		145125 RNA14_SCHPO (306-820): 2.78e-35: 145: 10.56		YKCG_SCHPO (43-205): 1.2e-33: 125: 19.63
+	Sc
		996591 CLF1_YEAST (4-377): 2.18e-12: 72.7: 11.71		NCBP2_YEAST (1-208): 1.82e-52: 169: 100.00
+	Sp
		145123 RNA14_SCHPO (306-820): 2.78e-35: 145: 10.56		CTF1_SCHPO (45-156): 1.65e-22: 95.1: 18.75
+	Hs
		300087 PRP6_HUMAN (459-856): 1.36e-23: 109: 12.94		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	Dm
		639847 SUF_DROME (537-825): 4.9e-09: 62.3: 10.71		Q86NL1_DROME (34-153): 2.78e-39: 141: 20.83
+	Hs
		1022314 CSTF3_HUMAN (524-837): 1.06e-10: 67.3: 8.66		CSTFT_HUMAN (35-153): 4.46e-34: 129: 18.33
+	Hs
		703378 CSTF3_HUMAN (524-837): 1.06e-10: 67.3: 8.66		CSTF2_HUMAN (35-153): 1.04e-33: 127: 17.50
+	Hs
		230326 ZC3H1_HUMAN (229-807): 2.13e-09: 63.9: 10.93		NCBP2_HUMAN (14-162): 4.13e-38: 130: 49.33
+	At
		1208870 CTF77_ARATH (16-392): 1e-15: 83.9: 10.85		CTF64_ARATH (41-137): 2.72e-27: 109: 25.00
+	Sc
		648430 RRP5_YEAST (572-839): 8.35e-22: 104: 15.96		NSR1_YEAST (34-143): 2.23e-14: 72.8: 20.91
+	Sc
		1015447 CLF1_YEAST (4-377): 2.18e-12: 72.7: 11.71		HSH49_YEAST (41-119): 2.34e-25: 99.7: 28.75
+	Hs
		1020325 CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80		ELAV2_HUMAN (4-155): 3.36e-22: 94.3: 16.13
+	Hs
		1058078 RRP5_HUMAN (76-379): 2.3e-22: 105: 9.12		RBM19_HUMAN (42-113): 4.9e-09: 57.4: 36.00
+	Mm
		665754 CTR9_MOUSE (302-856): 1.1e-11: 70.8: 9.75		PABP1_MOUSE (47-175): 1.38e-20: 90.9: 14.60
+	Hs
		230351 ZC3H1_HUMAN (229-807): 2.13e-09: 63.9: 10.93		PABP4_HUMAN (47-175): 3.25e-21: 92.8: 11.68