Interactor 1: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 11842115, 11805826, 16554755, 16429126, 19617314, 37968396, 21576257, 12509417
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071004 - U2-type prespliceosome
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 859
Sc

1 687
+ Sc
+ Sp
+ Dm
+ Hs
+ Hs
+ Sc
+ Sp
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024