Interactor 1: DOT1 (Q04089)
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (Disrupter of telomere silencing protein 1) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
Gene: DOT1

Interactor 2: DOT1 (Q04089)
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (Disrupter of telomere silencing protein 1) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
Gene: DOT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 21179020
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains DOT1~DOT1
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000725 - recombinational repair
GO:0000781 - chromosome, telomeric region
GO:0000786 - nucleosome
GO:0003677 - DNA binding
and 15 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 582
Sc

1 582
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024