HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17785777
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0051607 - defense response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 200
+	Hs
		978803 TF65_HUMAN (1-551): 0: 601: 100.00		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		587624 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		964497 RELB_HUMAN (3-461): 2.62e-154: 455: 40.00		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		587630 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		964498 RELB_HUMAN (3-461): 2.62e-154: 455: 40.00		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		961403 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		961404 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94