HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: TNIP2 (Q8NFZ5)
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
Gene: TNIP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

The method score is based on:

Property	Details
Experiments	27609421, 29084252, 14743216
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, tandem affinity purification
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0006954 - inflammatory response GO:0019901 - protein kinase binding and 4 others more... GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0070498 - interleukin-1-mediated signaling pathway GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	551
Hs

1	429

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024