Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: SETD6 (Q8TBK2)
N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6)
Gene: SETD6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.55 0.633

The method score is based on:

Property Details
Experiments 21131967, 21515635
Identification Methods affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0050727 - regulation of inflammatory response
GO:0051059 - NF-kappaB binding
Homologous interactions 0

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Last updated: 15 Jul 2024