HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: DPF1 (Q92782)
Zinc finger protein neuro-d4 (BRG1-associated factor 45B) (BAF45B) (D4, zinc and double PHD fingers family 1)
Gene: DPF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	22334708
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 387
+	Hs
		978830 TF65_HUMAN (1-551): 0: 601: 100.00		DPF3_HUMAN (1-382): 4.01e-107: 321: 68.21
+	Hs
		978831 TF65_HUMAN (1-551): 0: 601: 100.00		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		587652 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		DPF1_HUMAN (1-387): 8.5e-129: 377: 100.00
+	Hs
		587653 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		DPF3_HUMAN (1-382): 4.01e-107: 321: 68.21
+	Hs
		981669 REL_HUMAN (12-523): 3.56e-165: 484: 41.64		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		587654 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		978822 TF65_HUMAN (1-551): 0: 601: 100.00		PHF10_HUMAN (214-374): 5.77e-33: 130: 34.15
+	Hs
		964509 RELB_HUMAN (3-461): 2.62e-154: 455: 40.00		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		152631 TF65_HUMAN (1-551): 0: 601: 100.00		KMT2D_HUMAN (197-380): 3.16e-27: 116: 24.73
+	Hs
		961414 NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		587548 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		CHD3_HUMAN (63-374): 3.32e-52: 189: 15.71
+	Hs
		1035263 NFAC2_HUMAN (4-527): 1.26e-110: 353: 18.97		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		587646 NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51		PHF10_HUMAN (214-374): 5.77e-33: 130: 34.15
+	Dm
		1179549 NFKB1_DROME (19-402): 1.17e-109: 351: 28.71		Q7K3G5_DROME (5-378): 4.06e-72: 235: 30.88
+	Hs
		318000 NFAC1_HUMAN (1-503): 2.8e-93: 307: 18.89		REQU_HUMAN (1-384): 3.36e-88: 273: 57.86
+	Hs
		1035235 NFAC2_HUMAN (4-527): 1.26e-110: 353: 18.97		CHD4_HUMAN (63-386): 1.11e-44: 167: 13.48
+	Hs
		1035276 NFAC2_HUMAN (4-527): 1.26e-110: 353: 18.97		UHRF1_HUMAN (86-386): 8.53e-35: 137: 16.51
+	Hs
		317969 NFAC1_HUMAN (1-503): 2.8e-93: 307: 18.89		CHD4_HUMAN (63-386): 1.11e-44: 167: 13.48