Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 17434128, 10454579, 25314079, 25733689, 12163591, 15140884, 11931769, 9548485, 9096323, 12789342, 18241676, 9659924, 14597638, 17296604, 17138826, 15806143, 21483817, 36629882, 10542243, 10235267 and 3 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001223 - transcription coactivator binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 10 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 551
Hs

1 2442
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+ Dm
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Last updated: 15 Jul 2024