HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 9990853, 25900982, 28514442, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0038061 - non-canonical NF-kappaB signal transduction
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 551
Hs

1 605
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Last updated: 15 Jul 2024