HitPredict

Interactor 1: TF65 (Q04207)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: Rela

Interactor 2: IKBA (Q9Z1E3)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha)
Gene: Nfkbia

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 21098220, 20634424, 16163708, 16928772, 20740013, 14636585, 16166627, 10801847, 10400699, 15470505, 18276832, 9405619, 16226509, 19931640, 20685965, 23086447, 23850221, 17254973, 21706061, 15102471 and 1 others

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Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~RHD_dimer
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
GO:0031625 - ubiquitin protein ligase binding
and 12 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 549
Mm

1 314
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024