HitPredict

Interactor 1: DHR1 (Q04217)
Probable ATP-dependent RNA helicase DHR1 (EC 3.6.4.13) (DEAH box RNA helicase DHR1) (Extracellular mutant protein 16)
Gene: ECM16

Interactor 2: NOP58 (Q12499)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.743

Property	Details
Experiments	29263326, 33326748, 35385737, 37968396, 12068309, 16429126, 21558325, 12150911
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome GO:0032040 - small-subunit processome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1267 Sc			1 511
+	Sc
		979089 DHR1_YEAST (1-1267): 0: 1081: 100.00		NOP56_YEAST (1-473): 1.17e-170: 493: 37.58
+	Hs
		133529 DHX57_HUMAN (104-1236): 0: 788: 18.93		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133249 DHX16_HUMAN (154-1213): 0: 784: 20.78		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133459 DHX9_HUMAN (155-1197): 0: 779: 20.97		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133559 DHX37_HUMAN (233-1255): 0: 757: 34.14		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133674 DHX33_HUMAN (373-1183): 0: 708: 28.59		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133547 DHX30_HUMAN (320-1184): 9.8e-170: 538: 23.40		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Sc
		589436 PRP2_YEAST (704-915): 4.62e-40: 162: 38.68		PRP31_YEAST (167-462): 3.33e-70: 234: 18.27