HitPredict

Interactor 1: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Interactor 2: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25681446, 18775313
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043130 - ubiquitin binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 618
+	Hs
		299366 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		BIRC2_HUMAN (1-618): 0: 702: 100.00
+	Hs
		979290 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03
+	Hs
		957797 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38
+	Hs
		1264870 UBP13_HUMAN (2-162): 3.18e-36: 139: 22.98		RFFL_HUMAN (567-618): 2.51e-17: 85.8: 42.31
+	Hs
		800606 UBP5_HUMAN (1-162): 6.44e-32: 127: 25.31		RFFL_HUMAN (567-618): 2.51e-17: 85.8: 42.31