HitPredict

Interactor 1: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 33277362, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~UBA, UBA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 624
+	Hs
		979375 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		299484 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1355405 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1267630 UBXN4_HUMAN (22-293): 5.83e-45: 160: 24.30		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1273584 UBP13_HUMAN (2-162): 3.18e-36: 139: 22.98		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		299490 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Ce
		107537 UBXN4_CAEEL (17-294): 1.48e-46: 164: 24.20		UBQL_CAEEL (27-621): 1.63e-110: 343: 33.73
+	Hs
		803499 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803809 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		803679 UBP13_HUMAN (2-162): 3.18e-36: 139: 22.98		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		924437 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Dm
		547957 Q9VSC5_DROME (4-293): 2.83e-47: 162: 35.74		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33
+	Hs
		800571 UBP5_HUMAN (1-162): 6.44e-32: 127: 25.31		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		924089 UBS3B_HUMAN (5-73): 4.15e-16: 80.4: 46.38		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Dm
		547964 Q9VZU7_DROME (3-131): 2.05e-21: 96.2: 23.26		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33