HitPredict

Interactor 1: VTI1 (Q04338)
t-SNARE VTI1 (Qb-SNARE VTI1) (VPS10-interacting protein 1) (Vesicle transport v-SNARE protein VTI1)
Gene: VTI1

Interactor 2: TLG2 (Q08144)
t-SNARE affecting a late Golgi compartment protein 2 (Syntaxin TLG2)
Gene: TLG2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 9427746, 10397773, 11739407, 11432826, 23776654
Identification Methods coimmunoprecipitation, affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~V-SNARE_C
Common GO terms GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 217
Sc

1 397
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024