HitPredict

Interactor 1: PUF6 (Q04373)
Pumilio homology domain family member 6
Gene: PUF6

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	27458021, 31779129, 16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 656 Sc			1 291
+	Sc
		733930 PUF6_YEAST (1-656): 3.91e-168: 497: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Hs
		1073232 PUM3_HUMAN (22-654): 8.46e-139: 421: 22.88		BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91
+	Sc
		755327 PUF6_YEAST (1-656): 3.91e-168: 497: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		754906 PUF6_YEAST (1-656): 3.91e-168: 497: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		979472 PUF6_YEAST (1-656): 3.91e-168: 497: 100.00		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17
+	Hs
		1073269 PUM3_HUMAN (22-654): 8.46e-139: 421: 22.88		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87