HitPredict

Interactor 1: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 11743162, 18467557, 19841731, 22940862, 20647997
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, two hybrid pooling approach, pull down, filter binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Myosin_head~Myosin_head, SH3_1~SH3_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005933 - cellular bud
and 20 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1219
Sc

1 1219
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+ Hs
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024