HitPredict

Interactor 1: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Interactor 2: SKM1 (Q12469)
Serine/threonine-protein kinase SKM1 (EC 2.7.11.1) (Protein kinase 75490 D)
Gene: SKM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19841731
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 Sc			1 655
+	Sc
		976584 MYO5_YEAST (1-1219): 0: 1126: 100.00		STE20_YEAST (123-653): 9.08e-123: 388: 32.53
+	At
		98846 MYO17_ARATH (6-1105): 0: 1111: 27.49		KIN10_ARATH (356-651): 1.8e-122: 375: 22.00
+	Sc
		730591 MYO3_YEAST (1-1205): 0: 1087: 72.08		STE20_YEAST (123-653): 9.08e-123: 388: 32.53
+	Hs
		725152 MYH10_HUMAN (2-1099): 0: 1013: 24.07		PAK2_HUMAN (120-652): 1.08e-142: 427: 35.84
+	Hs
		681696 MYH9_HUMAN (7-1119): 0: 1017: 23.96		AKT1_HUMAN (245-654): 3.78e-123: 375: 19.81
+	Hs
		522609 MYH7_HUMAN (2-949): 0: 1030: 28.20		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		522610 MYH7_HUMAN (2-949): 0: 1030: 28.20		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Hs
		528408 MYH8_HUMAN (5-830): 0: 1012: 31.37		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		528409 MYH8_HUMAN (5-830): 0: 1012: 31.37		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Hs
		528369 MYH6_HUMAN (5-830): 0: 1008: 30.73		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		1023137 MYH2_HUMAN (5-830): 0: 1006: 31.42		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		528371 MYH6_HUMAN (5-830): 0: 1008: 30.73		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Hs
		1027452 MYH2_HUMAN (5-830): 0: 1006: 31.42		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Hs
		522545 MYH1_HUMAN (5-830): 0: 1002: 30.57		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		522546 MYH1_HUMAN (5-830): 0: 1002: 30.57		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Sc
		819908 MYO5_YEAST (1-1219): 0: 1126: 100.00		CLA4_YEAST (5-353): 7.42e-49: 185: 35.80
+	Sc
		730573 MYO3_YEAST (1-1205): 0: 1087: 72.08		CLA4_YEAST (5-353): 7.42e-49: 185: 35.80
+	Hs
		117684 MYO1C_HUMAN (31-736): 0: 570: 41.82		STK3_HUMAN (335-654): 5.79e-115: 355: 33.13
+	Hs
		214695 MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72		AKT3_HUMAN (237-654): 2.74e-123: 375: 19.07
+	Hs
		682219 MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31		AKT2_HUMAN (245-654): 7.43e-125: 380: 19.67