HitPredict

Interactor 1: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.830

The method score is based on:

Property	Details
Experiments	25049393, 11340157, 15361857
Identification Methods	affinity chromatography technology, coimmunoprecipitation, far western blotting
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	MIF4G~MIF4G, MIF4G~MIF4G_like, MIF4G~MIF4G_like_2
Common GO terms	GO:0002191 - cap-dependent translational initiation GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 4 others more... GO:0005829 - cytosol GO:0006446 - regulation of translational initiation GO:0030307 - positive regulation of cell growth GO:0060090 - molecular adaptor activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	1599
Hs

1	790

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024