HitPredict

Interactor 1: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	26186194, 28514442, 33961781, 16541103, 24981860, 24248602
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005829 - cytosol GO:0006413 - translational initiation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1599 Hs			1 325
+	Mm
		1157647 IF4G1_MOUSE (1-1599): 0: 902: 88.52		EIF3I_MOUSE (1-325): 1.41e-92: 279: 99.39
+	Hs
		903152 IF4G1_HUMAN (1-1599): 0: 953: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		979963 IF4G1_HUMAN (1-1599): 0: 953: 100.00		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		203366 IF4G3_HUMAN (37-1599): 0: 715: 44.09		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		297832 K0754_HUMAN (250-760): 1.78e-09: 65: 16.89		BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72