Interactor 1: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Interactor 2: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 17353931, 29395067, 24981860, 24768540, 24248602, 11408474
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, pull down, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~MA3, Helicase_C~MA3, DEAD~MIF4G, Helicase_C~MIF4G
Common GO terms GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006413 - translational initiation
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024