HitPredict

Interactor 1: ERV41 (Q04651)
ER-derived vesicles protein ERV41
Gene: ERV41

Interactor 2: ERP1 (Q05359)
Protein ERP1
Gene: ERP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	37968396, 28183979
Identification Methods	affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030134 - COPII-coated ER to Golgi transport vesicle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 219
+	Hs
		1071860 ERGI3_HUMAN (1-334): 2.53e-133: 387: 23.20		TMED2_HUMAN (21-219): 3.34e-62: 194: 21.00
+	Sc
		698463 ERV41_YEAST (1-352): 1.51e-143: 411: 100.00		EMP24_YEAST (3-219): 3.44e-51: 166: 22.94
+	Sc
		763793 ERV46_YEAST (2-335): 2.8e-109: 326: 18.78		ERP1_YEAST (1-219): 8.35e-69: 211: 100.00
+	Hs
		1071816 ERGI2_HUMAN (1-320): 2.32e-109: 325: 27.96		TMED2_HUMAN (21-219): 3.34e-62: 194: 21.00
+	Sc
		873187 ERV41_YEAST (1-352): 1.51e-143: 411: 100.00		TMEDA_YEAST (5-219): 2.77e-26: 102: 16.67
+	Sc
		698414 ERV46_YEAST (2-335): 2.8e-109: 326: 18.78		EMP24_YEAST (3-219): 3.44e-51: 166: 22.94
+	Hs
		833291 ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72		TMEDA_HUMAN (20-219): 1.53e-65: 203: 19.00
+	Hs
		1071805 ERGI1_HUMAN (5-327): 1.18e-89: 272: 17.72		TMED2_HUMAN (21-219): 3.34e-62: 194: 21.00
+	Sc
		763784 ERV46_YEAST (2-335): 2.8e-109: 326: 18.78		TMEDA_YEAST (5-219): 2.77e-26: 102: 16.67