HitPredict

Interactor 1: ATP7A (Q04656)
Copper-transporting ATPase 1 (EC 7.2.2.8) (Copper pump 1) (Menkes disease-associated protein)
Gene: ATP7A

Interactor 2: LAMP3 (Q9UQV4)
Lysosome-associated membrane glycoprotein 3 (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD antigen CD208)
Gene: LAMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031901 - early endosome membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1500 Hs			1 416
+	Hs
		527411 ATP7A_HUMAN (1-1500): 0: 1436: 100.00		LAMP2_HUMAN (16-415): 1.55e-144: 419: 18.47
+	Hs
		506979 ATP7A_HUMAN (1-1500): 0: 1436: 100.00		LAMP1_HUMAN (7-416): 5.41e-138: 402: 21.23
+	Hs
		393006 AT1A1_HUMAN (720-1472): 0: 576: 14.95		LAMP2_HUMAN (16-415): 1.55e-144: 419: 18.47
+	Hs
		393393 AT1A1_HUMAN (720-1472): 0: 576: 14.95		LAMP3_HUMAN (1-416): 1.85e-139: 406: 100.00
+	Hs
		392999 AT1A1_HUMAN (720-1472): 0: 576: 14.95		LAMP1_HUMAN (7-416): 5.41e-138: 402: 21.23
+	Hs
		527324 ATP7B_HUMAN (1-571): 2.75e-100: 355: 26.26		LAMP2_HUMAN (16-415): 1.55e-144: 419: 18.47
+	Hs
		727463 ATP7B_HUMAN (1-571): 2.75e-100: 355: 26.26		LAMP3_HUMAN (1-416): 1.85e-139: 406: 100.00
+	Dm
		530321 ATNA_DROME (720-1466): 1.28e-179: 565: 15.52		Q9V9S0_DROME (199-413): 5.4e-57: 191: 21.49