HitPredict

Interactor 1: ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)
Gene: ERB1

Interactor 2: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 37968396, 23209026
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 807 Sc			1 1729
+	Hs
		903230 WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		1058048 NLE1_HUMAN (706-806): 8.16e-21: 98.6: 17.82		RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89
+	Hs
		672800 WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53		CDC27_HUMAN (1106-1729): 6.38e-66: 243: 12.30
+	Hs
		174768 WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		209476 PLRG1_HUMAN (581-806): 1.32e-46: 176: 14.90		CRNL1_HUMAN (1208-1729): 7.73e-38: 156: 11.75
+	Hs
		209486 PLRG1_HUMAN (581-806): 1.32e-46: 176: 14.90		SYF1_HUMAN (1511-1727): 3.02e-18: 93.6: 12.31
+	Hs
		300095 WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16
+	Hs
		175177 TBL1R_HUMAN (708-806): 5.17e-16: 84: 20.00		OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33
+	Hs
		300222 FBXW7_HUMAN (717-807): 4.36e-11: 68.6: 22.83		PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16