HitPredict

Interactor 1: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27591049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 956
+	Hs
		445127 K1C16_HUMAN (80-410): 1.7e-159: 460: 79.28		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		359420 K1C14_HUMAN (82-430): 1.15e-151: 440: 82.40		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		444486 K1C19_HUMAN (77-394): 1.39e-146: 424: 73.59		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		531514 K1C13_HUMAN (73-398): 8.48e-143: 417: 70.73		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1303672 K1C12_HUMAN (78-426): 1.31e-127: 379: 60.81		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		531428 K1C10_HUMAN (79-389): 1.15e-123: 372: 69.75		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		280728 KRT34_HUMAN (77-395): 9.16e-117: 348: 58.62		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1189699 K1C25_HUMAN (78-424): 3.72e-114: 343: 53.13		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1189663 K1C27_HUMAN (4-431): 3.48e-107: 326: 49.55		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1110348 K2C71_HUMAN (27-398): 3.87e-77: 250: 23.00		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1062069 K2C72_HUMAN (35-398): 2.83e-76: 248: 24.59		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		380523 K2C6B_HUMAN (50-414): 2.7e-73: 241: 23.43		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		531636 K2C5_HUMAN (50-398): 1.34e-72: 240: 25.07		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		359537 K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343331 KRT84_HUMAN (135-430): 4.3e-11: 66.7: 16.83		CYLD_HUMAN (1-956): 0: 1872: 100.00