HitPredict

Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Interactor 2: ZFP41 (Q8N8Y5)
Zinc finger protein 41 homolog (Zfp-41)
Gene: ZFP41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2471 Hs			1 198
+	Hs
		980426 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZSCA2_HUMAN (2-197): 6.84e-102: 307: 33.99
+	Hs
		980462 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN397_HUMAN (28-198): 7.29e-96: 289: 40.11
+	Hs
		980477 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN480_HUMAN (19-198): 1.97e-83: 258: 36.90
+	Hs
		563705 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZKSC1_HUMAN (5-197): 5.16e-73: 231: 38.19
+	Hs
		980472 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN431_HUMAN (30-198): 1.55e-72: 231: 39.43
+	Hs
		485343 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		GLI4_HUMAN (3-196): 1.15e-68: 215: 36.32
+	Hs
		980554 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN358_HUMAN (1-139): 2.59e-65: 212: 21.23
+	Hs
		980539 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN430_HUMAN (67-198): 1.17e-57: 192: 42.42
+	Hs
		980446 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN664_HUMAN (87-198): 1.57e-25: 100: 48.21
+	Hs
		980566 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN629_HUMAN (1-194): 1.09e-23: 99.6: 15.18
+	Hs
		565090 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZNF7_HUMAN (84-139): 4.99e-12: 65.9: 53.57
+	Hs
		254652 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZN623_HUMAN (103-193): 6.58e-12: 65.5: 38.46
+	Hs
		980381 NOTC2_HUMAN (22-2471): 0: 1386: 100.00		ZKSC8_HUMAN (1-35): 9.66e-12: 64.9: 22.22
+	Hs
		724348 FBN1_HUMAN (201-1638): 9.66e-69: 261: 18.41		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		1219780 ANKH1_HUMAN (1868-2428): 1.04e-68: 261: 13.64		ZNF34_HUMAN (6-198): 3.17e-79: 247: 36.00
+	Hs
		724383 FBN2_HUMAN (474-1671): 8.72e-37: 155: 16.92		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		1237988 NOTC3_HUMAN (1931-2465): 6.29e-11: 70.7: 16.82		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		563640 DNER_HUMAN (1171-1439): 9.13e-25: 114: 30.18		ZNF24_HUMAN (132-198): 5.65e-13: 68.2: 49.25