Interactor 1: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2
Interactor 2: JAG2 (Q9Y219)
Protein jagged-2 (Jagged2) (hJ2)
Gene: JAG2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10958687 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~EGF_CA, DSL~EGF_CA, EGF_CA~EGF_CA, EGF_CA~MNNL |
| Common GO terms | GO:0001701 - in utero embryonic development GO:0005112 - Notch binding GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007219 - Notch signaling pathway |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
