Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: TLE2 (Q04725)
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)
Gene: TLE2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 24981860, 33961781, 9874198, 37689310
Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TLE_N~TLE_N, WD40~WD40
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0007165 - signal transduction
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 770
Hs

1 743
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024