Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 16314515, 33961781, 28514442, 24981860
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TLE_N~TLE_N, WD40~WD40
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0016055 - Wnt signaling pathway
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 770
Hs

1 773
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024