Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 17353931, 33961781, 22354967
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TLE_N~TLE_N
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0016055 - Wnt signaling pathway
GO:0045892 - negative regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 770
Hs

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Last updated: 15 Jul 2024